Product Name:Letrozole
CAS No:112809-51-5
Molecular formula: C17H11N5
Molecular weight: 285.3
Appearance:white powder
Purity: 99%
Packing: sample 10g,100g500g,1kg
Storage: Shading, confined preservation
Letrozole is a non steroidal selective third-generation aromatase inhibitor. The structure and activity of the compound are very similar to the structure and activity of Ahna's trazole, and the clinical use is also consistent. The US prescription guidelines for letrozole suggest that it be used to treat breast cancer with estrogen receptor positive or estrogen receptor unknown postmenopausal women (not sure if cancer is reacting to estrogen). After estrogen receptor antagonists such as tamoxifen fail to cause the required response, they are usually used as the second therapeutic agent, and sometimes as the first therapeutic agent according to the situation. Male bodybuilders and athletes have found the ability of letrozole to reduce anabolic / androgen steroid related estrogen side effects, such as male breast development, fat accumulation and increased moisture.
Letrozole is one of a series of new drugs for aromatase inhibitors. It is the most effective estrogen lowering drug developed so far, and has a stronger effect than non selective first generation aromatase inhibitors such as Tesla and amlumide. The dose of letrozole per tablet is 2.5 mg, which is sufficient to reduce estrogen levels by an average of 78% during clinical use according to product information. The drug also generally maintains fairly effective properties at lower doses. The instructions of the product point out that the low and medium doses in clinical studies are 0.1 and 0.5 mg respectively, which can produce 75% and 78% estrogen inhibition in many patients, respectively. The recommended dose also caused the required level of inhibition in almost all patients. Therefore, many people may not need a dose of 2.5mg and only need half a tablet to obtain good results.
The recommended dose for medical treatment is 2.5mg per day to reduce the increase of estrogen in anabolism. It only needs 1.25mg per week for testosterone below 800mg and body fat below 15% to suppress estrogen. It usually needs 2.5mg letrozole per day for testosterone above 1000mg per week. The specific dose is adjusted according to different physique. Please refer to the specific situation for specific analysis.
letrozole Applications:
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.In fact,it would prove to be virtually identical to the already popular AI in Arimidex .Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.
Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.